Francis Crick

Biology English 1916 – 2004 386 quotes

Co-discovered DNA structure, central dogma of biology

Quotes by Francis Crick

We were the first persons to see the structure of DNA as it really was.

Attributed remark on discovery

The discovery of the double helix was, in large part, due to the unacknowledged contribution of Rosalind Franklin.

Attributed later reflection

It seems likely that most if not all the genetic information in any organism is carried by nucleic acid—usually by DNA, although certain small viruses use RNA as their genetic material.

On Protein Synthesis 1957

The Center Dogma. This states that once 'information' has passed into protein it cannot get out again.

On Protein Synthesis 1958

The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However, one would certainly expect such triplets to be in a minority.

General Nature of the Genetic Code 1961

I think the odds are against there being life elsewhere, but I'm not sure.

Attributed interview

The origin of life appears to be almost a miracle, so many are the conditions which would have had to be satisfied to get it going.

Life Itself: Its Origin and Nature 1981

An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle.

Life Itself: Its Origin and Nature 1981

Biologists must constantly keep in mind that what they see was not designed, but rather evolved.

Attributed principle

It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clicks into place.

What Mad Pursuit 1988

A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.

Attributed remark

The major credit I think Jim and I deserve... is for selecting the right problem and sticking to it.

What Mad Pursuit 1988

We have discovered the secret of life!

Attributed exclamation at The Eagle pub 1953

The structure was too pretty not to be true.

On the DNA double helix

I went home and told Odile that we seemed to have made a big discovery.

Letter 1953

While the double helix has a certain symmetry, the two chains are not identical, but complementary.

Molecular Structure of Nucleic Acids 1953

You, your joys and your sorrows, your memories and your ambitions, your sense of personal identity and free will, are in fact no more than the behavior of a vast assembly of nerve cells and their associated molecules.

The Astonishing Hypothesis 1994

The Astonishing Hypothesis is that 'You', your joys and your sorrows, your memories and your ambitions, your sense of personal identity and free will, are in fact no more than the behavior of a vast assembly of nerve cells and their associated molecules.

The Astonishing Hypothesis 1994

The scientific belief is that our minds—the behavior of our brains—can be explained by the interactions of nerve cells (and other cells) and the molecules associated with them.

The Astonishing Hypothesis 1994

It is inherently unlikely that anything as complex as a nervous system could be completely understood in the near future.

Thinking about the Brain 1979