It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body.
Discovery of penicillin
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"I was not a great scientist, but I was a careful observer."
Strange & Unusual"The accidental contamination of my cultures by a mold was not an unusual event in a bacteriological laboratory. What was unusual was my decision to investigate the mold."
Strange & Unusual"It is the lone worker who makes the first advance in a subject; the details may be worked out by a team, but the prime idea is due to enterprise, thought, and perception of an individual."
Strange & Unusual"I was not looking for penicillin when I discovered it. I was looking for a better antiseptic."
Shocking"I did not invent penicillin. Nature did that. I only discovered it by accident."
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