William Harvey — "The heart is the beginning of life; the sun of the microcosm, even as the sun in…"

The heart is the beginning of life; the sun of the microcosm, even as the sun in his turn might well be designated the heart of the world; for it is the heart by whose virtue and pulse the blood is moved, perfected, made apt to nourish, and is preserved from corruption and coagulation; it is the household divinity which, discharging its function, nourishes, cherishes, quickens the whole body, and is indeed the foundation of life, the source of all action.
William Harvey — William Harvey Early Modern · Blood circulation

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From 'De Motu Cordis' (1628), Chapter 8. A profound metaphorical and physiological description of the heart's central role.

Date: 1628

Philosophical

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